Methodology
From retrieval to a traceable clinical evidence trail.
Evidence Bridge is designed as a visible system, not an opaque answer box.
How evidence is retrieved
Evidence Bridge queries PubMed, Europe PMC, ClinicalTrials.gov, medication intelligence, terminology, and regional guidance sources in parallel.
How study type is identified
Publication metadata and source-provided study types are used to distinguish reviews, meta-analyses, trials, guidelines, and other evidence.
How Evidence Strength is calculated
A transparent screening signal currently classifies systematic reviews and meta-analyses as High; trials, guidelines, and reviews as Moderate; and other publication types as Low.
How patient characteristics are matched
Supplied context is compared with population details reported in each publication across age, sex, severity, renal function, previous treatment, and population representation.
How applicability is calculated
High means 4 or more reported matches, Moderate means 2-3, and Low means 0-1 or no patient profile. This is not a formal certainty grade.
How disagreements are identified
The synthesis model is instructed to preserve conflicts, uncertainty, study design, and applicability limits rather than collapse disagreement into a single claim.
How synthesis is generated
Retrieved passages are supplied to a closed-book model, then claims are checked against their cited passages in a second verification pass. Unsupported claims are removed.
Evidence Strength and Patient Applicability are screening signals for review. They do not replace clinical judgment, formal evidence-certainty frameworks, guidelines, or independent validation.